What effect on hippocampal cells have stress hormones had in recent studies described

Module 2 – Case
CHRONIC STRESS AND BEHAVIORAL RESPONSE
STOP!!! BEFORE YOU PROCEED, BE YOU MUST HAVE READ THE HOME PAGE AND
VIEWED ALL LINKS AND TUTORIALS!!! You will need this information
to complete this Case Assignment.
Assignment Overview
Cortisol is an important hormone that is released in the stress
response. In this module assignment, we will look at this hormone more closely
to investigate:
1. the molecular
composition of cortisol
2. the signaling
pathway that elicits the production and release of cortisol
3. the cellular-,
organ-, and organ system-level response that results from this cell signal
Case Assignment
Read the following articles:
.dartmouth.edu/fall-2010/the-physiology-of-stress-cortisol-and-the-hypothalamic-pituitary-adrenal-axis#.U-aGCONdVyw”>The Physiology
of Stress: Cortisol and the Hypothalamic-Pituitary-Adrenal Axis. Randall, M. 2011.
Dartmouth Undergraduate Journal of Science.
and
.trident.edu/content/enforced/41638-ANT100-FAL2014-1/ptsd-and-cortisol.pdf?_&d2lSessionVal=qEkbHmHpME0P9etqqmR6oH4E9&ou=41638″>The
Relationship between Traumatic Stress, PTSD and Cortisol. Delaney, E. Naval
Center for Combat & Operational Stress Control.
After reading these articles, develop a 1015 slide presentation in the
following format.
Slides 1 and 2: The cascade of hormonal signals described by
the section titled Neurochemistry of Stress of the Randall (2011) article.
Use simple ovals or circles to depict the regions that release specific
hormones in the hormone cascade that results in the release of cortisol. Label
the hormones and regions and organs involved using textboxes (both options
appear in the Insert tab of the PowerPoint program).
Slides 3 and 4: Label and diagram the kidney and adrenal
gland. Include the following:

Adrenal gland: cortex and medulla; regions associated with hormone
production and release; hormones released in each region

Kidney: cortex and medulla; region of water absorption and filtering;
region of urine collection
Slide 5: Diagram and label the HPA axis. Include the hormones released by
each component and their effect on the target organ(s).
Slide 6: Using your diagram from Slide 5, include the location of the
hippocampus and the negative feedback loop that occurs when the hippocampus
detects high cortisol levels. In the notes section, include a brief description
of the effects associated with elevated cortisol exposure to the hippocampus.
Slide 7: Using bulleted points, list factors that exacerbate the stress
response through activation of the HPA axis.
Slide 810: Do some additional research on PTSD. Diagram the regions of the
brain believed to be involved with symptoms of PTSD. Explain the relationship
between PTSD and depression and include relevant regions of the brain in your
labeled regions.
Slides 1113: In bulleted points, summarize the varied findings in the studies
described in the article, The Relationship between Traumatic Stress, PTSD and
Cortisol. Include the relationships found between cortisol levels and
individuals with PTSD. In the notes include some explanations from the article
for the variability in cortisol levels in these individuals. Explain the
limitations of these studies mentioned by the author at the end of the article.
Slides 14 and 15: references cited, additional notes if
necessary
Assignment Expectations
For this Case Assignment you will develop a PowerPoint presentation that
is approximately 15 slides in length and addresses the requirements outlined
above. Place the text containing the answers to the questions above in the
Notes section of your slide presentation. Reference all of your answers in your
Notes sections with citations, such as (Murray 2014). Your slides should
contain labeled images that illustrate the text that you included in your Notes
sections. Do a Google search that includes the term image to find diagrams of
the required organs and systems (e.g., search for adrenal gland image).
Provide the website or reference used for each labeled image. Be sure your last
slide is a references slide that contains the full references cited on your
slides. Many resources are provided for you. Include these in your references
section. This assignment should not require much independent research.
Module 2 – SLP
CHRONIC STRESS AND BEHAVIORAL RESPONSE
Continue your investigation of
the effects of stress on brain function and behavior. Read more about the
hippocampus, amygdala, and prefrontal cortex in these articles:
.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain, in Psychology
Today
.rockefeller.edu/mcewen/stresshippo”>Stress Effects on Structure and Function
of Hippocampus, by the Rockefeller University
Answer the following questions
in paragraph format to write an essay about the findings reported by these
articles:
Introduction
Paragraph:
First, do some research on how
the.mcgill.ca/flash/d/d_04/d_04_cr/d_04_cr_peu/d_04_cr_peu.html”>amygdala,
hippocampus, and prefrontal cortex communicateand result in normal behavioral
response. You will begin your reading on the amygdala by following this link.
After reading this section, click on.mcgill.ca/flash/i/i_04/i_04_cr/i_04_cr_peu/i_04_cr_peu.html”>several other
structures in the brainat the end of the page to read about
the interactions between these three regions. Briefly describe this pathway and
the behavior that results from the interaction of these regions using the
format and requirements outlined below.
Body
Paragraph 1
Summarize the effects of
glucocorticoids on the hippocampus and prefrontal cortex reported in the
article.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain.
Body
Paragraphs 2 and 3
What effect on hippocampal
cells have stress hormones had in recent studies described by.rockefeller.edu/mcewen/stresshippo”>Stress Effects on Structure and Function
of Hippocampus? What effect have they had on the
amygdala in studies? What are the implications of these effects? HINT: What are
the functions of the regions and how might they be affected by changes in their
structure?
Body
Paragraph 4
What is neurogenesis and where
does it occur in the brain? What effect on the regeneration of hippocampal
cells is reported in this article? What is the mechanism?
Conclusion
Paragraph 1
Summarize the effects of
cortisol on this pathway by describing how PTSD can result from perpetuated
cortisol release and how this can result in depression by activating and/or
reinforcing.mcgill.ca/flash/a/a_08/a_08_p/a_08_p_dep/a_08_p_dep.html”>depression
pathways.
Conclusion
Paragraph 2
Describe the methods proposed
to counteract the negative effects of chronic stress in.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain.
SLP Assignment Expectations
For this assignment, write an
essay using the outline above. You are provided with many scholarly references
to complete this assignment. Include a References section that lists these and
any additional sources you used (refer to the Background page). For any
additional research you are required to do to complete your assignment, please
use scholarly references such as a peer-reviewed journal article or a
government-sponsored or university-sponsored website. As you read through your
sources, take notes from your sources and then write your paper in your own
words, describing what you have learned from your research. Direct quotes
should be limited and must be designated by quotation marks. Paraphrased ideas
must give credit to the original author, for example (Murray, 2014).Direct
copying from homework help websites will not receive credit.
Module 2 – CaseCHRONIC STRESS AND BEHAVIORAL RESPONSESTOP!!! BEFORE YOU PROCEED, BE YOU MUST HAVE READ THE HOME PAGE AND
VIEWED ALL LINKS AND TUTORIALS!!! You will need this information
to complete this Case Assignment.Assignment OverviewCortisol is an important hormone that is released in the stress
response. In this module assignment, we will look at this hormone more closely
to investigate:1. the molecular
composition of cortisol2. the signaling
pathway that elicits the production and release of cortisol3. the cellular-,
organ-, and organ system-level response that results from this cell signalCase AssignmentRead the following articles:.dartmouth.edu/fall-2010/the-physiology-of-stress-cortisol-and-the-hypothalamic-pituitary-adrenal-axis#.U-aGCONdVyw”>The Physiology
of Stress: Cortisol and the Hypothalamic-Pituitary-Adrenal Axis. Randall, M. 2011.
Dartmouth Undergraduate Journal of Science.and.trident.edu/content/enforced/41638-ANT100-FAL2014-1/ptsd-and-cortisol.pdf?_&d2lSessionVal=qEkbHmHpME0P9etqqmR6oH4E9&ou=41638″>The
Relationship between Traumatic Stress, PTSD and Cortisol. Delaney, E. Naval
Center for Combat & Operational Stress Control.After reading these articles, develop a 1015 slide presentation in the
following format.Slides 1 and 2: The cascade of hormonal signals described by
the section titled Neurochemistry of Stress of the Randall (2011) article.
Use simple ovals or circles to depict the regions that release specific
hormones in the hormone cascade that results in the release of cortisol. Label
the hormones and regions and organs involved using textboxes (both options
appear in the Insert tab of the PowerPoint program).Slides 3 and 4: Label and diagram the kidney and adrenal
gland. Include the following:
Adrenal gland: cortex and medulla; regions associated with hormone
production and release; hormones released in each region
Kidney: cortex and medulla; region of water absorption and filtering;
region of urine collectionSlide 5: Diagram and label the HPA axis. Include the hormones released by
each component and their effect on the target organ(s).Slide 6: Using your diagram from Slide 5, include the location of the
hippocampus and the negative feedback loop that occurs when the hippocampus
detects high cortisol levels. In the notes section, include a brief description
of the effects associated with elevated cortisol exposure to the hippocampus.Slide 7: Using bulleted points, list factors that exacerbate the stress
response through activation of the HPA axis.Slide 810: Do some additional research on PTSD. Diagram the regions of the
brain believed to be involved with symptoms of PTSD. Explain the relationship
between PTSD and depression and include relevant regions of the brain in your
labeled regions.Slides 1113: In bulleted points, summarize the varied findings in the studies
described in the article, The Relationship between Traumatic Stress, PTSD and
Cortisol. Include the relationships found between cortisol levels and
individuals with PTSD. In the notes include some explanations from the article
for the variability in cortisol levels in these individuals. Explain the
limitations of these studies mentioned by the author at the end of the article.Slides 14 and 15: references cited, additional notes if
necessaryAssignment ExpectationsFor this Case Assignment you will develop a PowerPoint presentation that
is approximately 15 slides in length and addresses the requirements outlined
above. Place the text containing the answers to the questions above in the
Notes section of your slide presentation. Reference all of your answers in your
Notes sections with citations, such as (Murray 2014). Your slides should
contain labeled images that illustrate the text that you included in your Notes
sections. Do a Google search that includes the term image to find diagrams of
the required organs and systems (e.g., search for adrenal gland image).
Provide the website or reference used for each labeled image. Be sure your last
slide is a references slide that contains the full references cited on your
slides. Many resources are provided for you. Include these in your references
section. This assignment should not require much independent research.Continue your investigation of
the effects of stress on brain function and behavior. Read more about the
hippocampus, amygdala, and prefrontal cortex in these articles:.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain, in Psychology
Today.rockefeller.edu/mcewen/stresshippo”>Stress Effects on Structure and Function
of Hippocampus, by the Rockefeller UniversityAnswer the following questions
in paragraph format to write an essay about the findings reported by these
articles:Introduction
Paragraph:First, do some research on how
the.mcgill.ca/flash/d/d_04/d_04_cr/d_04_cr_peu/d_04_cr_peu.html”>amygdala,
hippocampus, and prefrontal cortex communicateand result in normal behavioral
response. You will begin your reading on the amygdala by following this link.
After reading this section, click on.mcgill.ca/flash/i/i_04/i_04_cr/i_04_cr_peu/i_04_cr_peu.html”>several other
structures in the brainat the end of the page to read about
the interactions between these three regions. Briefly describe this pathway and
the behavior that results from the interaction of these regions using the
format and requirements outlined below.Body
Paragraph 1Summarize the effects of
glucocorticoids on the hippocampus and prefrontal cortex reported in the
article.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain.Body
Paragraphs 2 and 3What effect on hippocampal
cells have stress hormones had in recent studies described by.rockefeller.edu/mcewen/stresshippo”>Stress Effects on Structure and Function
of Hippocampus? What effect have they had on the
amygdala in studies? What are the implications of these effects? HINT: What are
the functions of the regions and how might they be affected by changes in their
structure?Body
Paragraph 4What is neurogenesis and where
does it occur in the brain? What effect on the regeneration of hippocampal
cells is reported in this article? What is the mechanism?Conclusion
Paragraph 1Summarize the effects of
cortisol on this pathway by describing how PTSD can result from perpetuated
cortisol release and how this can result in depression by activating and/or
reinforcing.mcgill.ca/flash/a/a_08/a_08_p/a_08_p_dep/a_08_p_dep.html”>depression
pathways.Conclusion
Paragraph 2Describe the methods proposed
to counteract the negative effects of chronic stress in.psychologytoday.com/blog/the-mindful-self-express/201208/how-prevent-stress-shrinking-your-brain”>How to Prevent
Stress from Shrinking Your Brain.For this assignment, write an
essay using the outline above. You are provided with many scholarly references
to complete this assignment. Include a References section that lists these and
any additional sources you used (refer to the Background page). For any
additional research you are required to do to complete your assignment, please
use scholarly references such as a peer-reviewed journal article or a
government-sponsored or university-sponsored website. As you read through your
sources, take notes from your sources and then write your paper in your own
words, describing what you have learned from your research. Direct quotes
should be limited and must be designated by quotation marks. Paraphrased ideas
must give credit to the original author, for example (Murray, 2014).Direct
copying from homework help websites will not receive credit.


 

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